Summary
This in vitro study investigated how well three different remineralizing toothpastes could rebuild artificially demineralized enamel of primary teeth. The following were compared:
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a conventional fluoride toothpaste
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Curasept
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BioMin
Additionally, there was an untreated control group and a group with artificial saliva.
Study Objective
The aim was to determine which product most effectively remineralizes early enamel lesions, thereby making the enamel harder, smoother, and richer in minerals again.
Method
40 extracted primary teeth were first artificially demineralized and then treated for 28 days. The effect was measured using the following procedures:
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Microhardness Test
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Surface Roughness
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Scanning Electron Microscopy with Energy Dispersive X-ray Spectroscopy (SEM-EDX)
Results
The study showed significant differences between the products:
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BioMin achieved the best results
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followed by Curasept
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the conventional fluoride toothpaste was also effective, but weaker
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artificial saliva alone yielded no relevant improvement
BioMin led to:
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the highest incorporation of calcium, phosphate, and fluoride
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the strongest increase in enamel hardness
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the most significant smoothing of the surface
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the best structural restoration under the microscope
Why BioMin performed better
The authors attribute this to the bioactive glass technology. BioMin releases calcium, phosphate, and fluoride ions over a longer period. This allows for more stable and deeper remineralization to develop than with conventional toothpaste.
Importance for pediatric dentistry
The results suggest that BioMin could be particularly interesting for early enamel lesions in children because primary teeth are thinner and less mineralized and therefore demineralize more quickly.
Limitation
The study was conducted in the laboratory. This means that the conditions in the mouth were only partially replicated. Clinical studies in children are still necessary to confirm the results in everyday life.
Conclusion
BioMin was the most effective agent for remineralizing demineralized enamel on primary teeth in this study, followed by Curasept and conventional fluoride toothpaste. The authors see this as a promising, non-invasive concept for treating early carious lesions in pediatric dentistry.