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International Journal of Recent Scientific Research Vol. 10, Issue, 05(A), pp. 32162-32167, May, 2019
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Efficacy of a Fluoro-Calcium-Phosphosilicate Toothpaste (Elsenz®) Compared to a Potassium Nitrate Toothpaste in the Treatment of Dentin Hypersensitivity. A Randomized Study.
Summary
This randomized controlled clinical trial investigated the effectiveness of a toothpaste with Fluoro-Calcium-Phosphosilicate (Elsenz®) compared to a potassium nitrate toothpaste and a normal control toothpaste for dentin hypersensitivity.
Aim
The aim was to investigate whether Elsenz can effectively reduce sensitive teeth and how it compares to a classic desensitizing toothpaste.
Method
- 60 patients with sensitive teeth
- 3 groups:
- Elsenz
- Potassium Nitrate
- Control toothpaste
- Assessment of sensitivity:
- with probe test (Probe Intensity Score)
- with cold air test
- with Schiff Score
- additionally, subjective pain reports from patients
- Measurement times:
- at baseline
- after 2 weeks
- after 8 weeks
Results
- Both test toothpastes, i.e. Elsenz and Potassium Nitrate, reduced dentin hypersensitivity significantly more than the control toothpaste.
- Over the 8-week period, a clear improvement was observed in both test groups.
- Between Elsenz and Potassium Nitrate, there was no significant difference in many parameters.
- The control group continued to show the highest sensitivity scores.
Significance
The study shows that Elsenz, as a novel active ingredient based on bioactive glass, can be effectively used against sensitive teeth. Its effect was comparable to potassium nitrate, an established standard active ingredient.
Limitations
- relatively small sample size
- 2 patients in the Elsenz group dropped out of the study
- placebo effects often play a role in sensitivity studies
Conclusion
Elsenz effectively reduced dentin hypersensitivity in this study and showed an effect comparable to potassium nitrate. Thus, the Fluoro-Calcium-Phosphosilicate technology appears to be an interesting alternative for sensitive teeth.