EVALUATION OF THE REMINERALISING EFFECT OF TOOTHPASTE BASED ON BIOACTIVE GLASS

Abstract

This in vitro study compared the remineralization effect of two bioactive glass toothpastes on artificially demineralized enamel:

• BioMin

• NovaMin with sodium fluoride

Aim

The study aimed to investigate which of the two bioactive glass toothpastes could better remineralize early enamel lesions.

Method

• 40 extracted premolars

• artificial creation of white spot lesions

• application of toothpastes as slurry twice daily for 2 weeks

• evaluation with:

  • Environmental Scanning Electron Microscopy (ESEM)

  • EDX analysis to measure calcium and phosphate

Results

• Both toothpastes showed a significant remineralization effect

• the mineral content of the demineralized enamel increased significantly in both groups

• between BioMin and NovaMin, there was mostly no statistically significant difference

• BioMin, however, showed higher phosphate values and was overall slightly superior

Significance

The study shows that both BioMin and NovaMin can remineralize early enamel lesions. BioMin might be slightly more effective, possibly due to its higher phosphate content, which promotes apatite formation.

Limitations

• pure laboratory study

• artificial conditions only partially replicated in the mouth

• further clinical studies are necessary

Conclusion

Both bioactive glass toothpastes showed good remineralization potential.
BioMin might be slightly superior to NovaMin and appears to be a promising option for treating early enamel lesions.