EVALUATION OF TREATMENT WITH BIOACTIVE GLASS FOR DENTIN HYPERSENSITIVITY

Abstract

This systematic review evaluated the efficacy of bioactive glasses in the treatment of dentin hypersensitivity. Randomized controlled trials from 2018 to 2022 comparing bioactive glass products for home or professional use with other desensitizing products were included.

Objective

To investigate the effectiveness of bioactive glass technologies – specifically:

• CSPS (Calcium Sodium Phosphosilicate, e.g., NovaMin)

• FCPS (Fluoro Calcium Phosphosilicate, e.g., BioMin F)

in sensitive teeth.

Method

• systematic search for clinical studies according to PRISMA criteria

• inclusion of adults with diagnosed dentin hypersensitivity

• only randomized controlled trials

• a total of 7 studies were included in the qualitative evaluation

Results

The review provides the following key statements:

• Bioactive glasses are effective in reducing dentin hypersensitivity

• CSPS showed similar results to established comparator products in the studies

• FCPS performed particularly well in terms of long-term effect in several studies

• overall, FCPS showed better symptom reduction than CSPS

Significance

The authors particularly rate FCPS as promising because it can promote more stable and acid-resistant mineral formation through fluoride, calcium, and phosphate. This suggests that it not only provides short-term relief but is also suitable for a more sustainable treatment.

Limitations

The authors also highlight some weaknesses of the existing studies:

• only few studies available

• partly heterogeneous methods

• differences in:

  • concentrations

  • study duration

  • test methods

  • control groups

• some studies had an increased risk of bias

Conclusion

The systematic review shows that bioactive glass toothpastes are effective against dentin hypersensitivity.
Specifically, FCPS could be the best long-term option, while CSPS is also effective but generally performs slightly weaker.