Abstract

This in-vitro study investigated how well BioMin-F can remineralize the enamel of primary teeth after artificial demineralization – compared to a conventional fluoride toothpaste (Signal®).

Objective

The aim was to determine whether BioMin-F causes greater remineralization in primary teeth than a standard toothpaste.

Method

• 30 extracted primary canines
• Divided into two groups:
  • BioMin-F
  • Signal
• Artificial demineralization over 69 hours
• Subsequent treatment with the respective toothpaste:
  • 2 times daily for 3 minutes
  • Over 15 days
• Evaluation using Vickers microhardness test

Results

• In both groups, microhardness significantly decreased after demineralization.
• After treatment, enamel hardness increased again in both groups.
• BioMin-F, however, achieved significantly higher microhardness values than Signal.
• Mean value after remineralization:
  • BioMin-F: 353.62
  • Signal: 300.62

Significance

The results suggest that BioMin-F can remineralize primary teeth more effectively than a conventional fluoride toothpaste. The authors attribute this to the longer release of fluoride, calcium, and phosphate from the bioactive glass.

Limitations

• Pure laboratory study
• Small sample size
• Artificially induced lesions instead of natural caries
• Further in-vivo studies are required

Conclusion

BioMin-F demonstrated significantly higher remineralization potential than a standard fluoride toothpaste on demineralized enamel of primary teeth in this study.
Thus, BioMin-F appears to be a promising option for the non-invasive treatment of early enamel lesions in primary dentition.