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J Oral Rehabil 2019 Jun 24. Epub 2019 Jun 24.
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A randomized clinical trial on the efficacy of 5% fluoro-calcium phosphosilicate-containing novel bioactive glass toothpaste

Summary

The document describes the scientific basis of BioMin technology and summarizes studies and mechanisms of action of bioactive glass toothpastes.

The focus is on a novel approach:
BioMin toothpastes contain bioactive glass with embedded fluoride, which slowly releases calcium, phosphate, and fluoride ions in the mouth. This creates a protective fluorapatite layer on the tooth surface that is significantly more acid-resistant than conventional tooth enamel.

A key advantage is the time-delayed release of active ingredients:

  • classic fluoride toothpastes only have a short-term effect
  • BioMin continues to work for up to 8–12 hours after brushing

The document highlights several clinical effects:

  • Remineralization of early enamel erosion
  • Closure of dentinal tubules → less sensitivity
  • possible antibacterial effect
  • long-term protection against acid attacks

Compared to older technologies (e.g., NovaMin), it is emphasized:

  • BioMin forms fluorapatite instead of hydroxyapatite
  • this creates a more stable and resistant protective layer

It is also highlighted:

  • small particles penetrate defects better
  • low abrasion → gentle on teeth
  • continuous buildup instead of just a short-term effect

Conclusion

BioMin is presented as “next generation” dental care technology that not only protects but actively regenerates and long-term stabilizes tooth enamel.

Lorenza Dahm